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KMID : 1039420200540040336
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Journal of Pathology and Translational Medicine
2020 Volume.54 No. 4 p.336 ~ p.339
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Pediatric granular cell tumor in the posterior wall of the larynx extending to the trachea
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Ahn Jung-Suk
Kim Na-Rae
Sun Yong-Han
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Abstract
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Granular cell tumor (GCT) is a slow-growing benign neoplasm that can be found in any organ. Pediatric laryngotracheal GCT is rare. We experienced a 6-year-old boy suffering from a barking cough and symptoms of stridor and croup for one month. Head and neck computed tomography revealed a protruding mass that occluded 60% of the airway lumen. Under the impression of hemangioma or papilloma, excision revealed a submucosal non-encapsulated mass. Histologically, the mass was composed of sheets of large polyhedralshaped tumor cells containing plump eosinophilic granular cytoplasm and centrally placed, small, bland-appearing nuclei. The tumor cells were positive for S-100 protein, and voluminous eosinophilic cytoplasm was stained by diastase-resistant periodic acid-Schiff. The present report describes a unique case of a huge pediatric laryngeal GCT extending to the subglottic trachea. We also review the clinical course of pediatric laryngotracheal GCT and emphasize the importance of diagnosing GCT in children.
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KEYWORD
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Granular cell tumor, Trachea, Larynx, Children
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